AuraSense™

AuraSense uses generative AI and automation to convert lengthy in-person neurology exams into short home based exercises

Startup based on IP developed by US Navy and by Dr. Charlot

Key Contributions:
- Raised $0.5M and secured 4 patents for innovative Neurorehabilitation technology
- Led development of core software for microcontroller and web interaction using C++, Python, Golang, and JavaScript
- Integrated generative AI and automation technologies for neurological assessments
- Led customer-facing requirements discovery, conducted product demos, and scoped projects, resulting in 5 contracts
- Negotiated contracts and intellectual property licenses with private companies and universities valued at $8M

Chief Executive Officer & Founder

CBio

CBio builds microfluidics tools for gene therapy and pathogen detection, reducing sample handling times from weeks to hours

Startup based on IP developed at Arizona State University and by Dr. Charlot 

Key Contributions:
- Raised $1.5M and secured 3 patents for innovative microfluidics technology
- Developed microfluidics consumables, analytical hardware, and software solutions
- Wrote computer vision and analytical instrument control libraries using C# and C++
- Designed electronic control boards using Altium, KiCad, and PCB design software from Sunstone and Advanced Circuits
- Managed partnerships with leading research institutions, resulting in 6 publications, $20M in grant funding, and groundbreaking discovery in neutralizing drug-resistant pathogens

FedTech

Private/Public DoD technology startup studio pairing entrepreneurs with DoD lab inventors

Key Contributions:
- Conducted 100+ customer discovery interviews to validate product-market fit
- Guided DoD technical teams in understanding and positioning complex technologies for market readiness
- Developed compelling business plan and pitch deck for AI-driven technologies, leading to 1st place and $20K prize at Demo Day

Entrepreneur in Residence

Arizona State University

Hayes Lab, in the Department of Chemistry, specializes in microfluidics to unlock novel therapy and diagnostic applications

Key Contributions:
- Implemented innovative microfluidics solutions resulting in 10-fold process improvements
- Developed C# application for fully automated experimentation and data acquisition
- Wrote software to perform particle image velocimetry to characterize virus and virus-like particles for vaccine research
- Mentored a team of 7 researchers, contributing to $5M in secured grants

Sr. Director of Translational Research (Hayes Lab - ISTBV274) / Entrepreneur In Residence

Ginkgo Bioworks, Inc.

World-leading synthetic biology company harnessing the power of living organisms to solve complex problems

Key Contributions:
- Scaled lab testing capabilities, achieving 100,000 daily sample testing throughput
- Developed C++ and Python software for robotic liquid handlers and peripheral components
- Collaborated with 3rd party firms to develop custom automation work cells

Sr. Automation Engineer

Participated in an awesome DoD based technology accelerator / startup studio where entrepreneurs are paired with inventors from DoD labs to perform customer discovery and market assessment for novel IP.

Phase I - Team 11: Graphene Fuel Sulfur Detection
Phase II - Team 5: Light-Talk / HALO

Hycor Biomedical LLC

Hardware and software debugging of robotics platform. I helped the organization obtain CE-Marking by diagnosing issues with their pre-production allergy diagnostics platform. I worked in the systems engineering division. CE-Marking achieved in Dec 2017.

Key Contributions: 
- Identified critical design and manufacturing defects in pre-production robotics instrumentation.
- Proposed and oversaw implementation of solutions to remove defects.
- Developed software script in C# to interpret proprietary debugger (byte code) to enable rapid identification automation failures.

Sr. Systems Engineer (Consultant)

Vala Sciences

Integration of collaborative robot to fully automate companies proprietary drug discovery platform. Developed and tested new consumable electrodes for companies Kinetic Image Cytometry (KIC) platform. The electrodes provide robust, non- biofouling electrical pacing (stimulation) of Cardiomyocytes, Neurons, and Stem Cells.

Startup based on IP developed at Sanford Burnham Preybs Institute. KIC is the commercial version of the prototype technology I developed for my PhD Thesis.

Key Contributions:
- Integrated Precise Automation PF400s collaborative SCARA robot with Vala’s cytometer, the CyteSeer IC200. Control GUI and interface drivers programmed using LabView. Customized Precise Automation’s open source GPL communication driver to enhance features required for robot integration.
- Redesigned Vala’s old electrical stimulation circuit board to enable multi-parameter sensing, bi-polar signal generation, amplitude control, and achieve pacing frequencies up to 15kHz. Designed circuit, schematic capture and layout using LTSpice, Altuim, and PCB Artist.
- Tested components on live Cardiomyocytes cultures to verify pacing performance.

Sr. Hardware | Software Development Engineer (Consultant)

Biological Dynamics

Biological Dynamics, Inc. is a leader in exosome isolation technology, offering simple, reliable, and automated isolation of exosomes for sensitive clinical tests that detect early stage cancer, treatment response, and cancer recurrence.

Startup based on IP developed at University of California, San Diego (UCSD)

Key Contributions:
- Raised $42M and secured 16 patents for innovative exosome technology
- Developed computer vision algorithms to quantify biomarkers related to early onset of cancer, enabling sensitive and reliable detection through blood-based samples
- Served as dedicated software engineer for all hardware control and analysis of proprietary platform for 7 years

Chief Technology Officer, President & Co-Founder

Sanford Burnham Prebys Medical Discovery Institute

Graduate Research Assistant in the Price Lab for Analytical and Quantitative Microscopy. Helped developed high content screening instrumentation for drug discovery related to oncology, heart disease and stem cell differentiation.

Key Contributions:
- Developed continuous scanning high content screening (HCS) instrument using laser autofocus, time delay and integrate (TDI) ccd technology, and multi-spectral LED illumination. HCS instrument used to increase chemical compound screening throughput for drug discovery. Software control written using Matlab, LabView, C++, and C#. 
- Developed 1st generation Kinetic Image Cytometer (KIC). Installed in stem cell core facility at Sanford Burnham Prebys Institute. Device used for automated capture and analysis of calcium transients in cell cultures for stem cell research, drug discovery and toxicity studies. Software control written in LabView and C#.
- Developed image analysis tools using C#, Matlab, Java, and LabView. Used open source software (CellProfiler, CyteSeer, and ImageJ) to quantify cellular morphology and dynamics.
- Presented scientific findings at conferences and generated unique IP for calcium transient image cytometry.
- Commercial variants of the instrumentation is currently being marketed and sold by Vala Sciences.
- Supervised to 2 masters students

Graduate Research Assistant

Dad, Husband, Friend of Earth Bringing Wellness to the Unreachable. Recognize the meaning in others! This is the way.

I'm a curious and impactful systems engineer using transistor magic, sound and light to build health and wellness tools.

Taplio

David Charlot, PhD, MSEng's Linkedin Analytics

Want to drive more opportunities from LinkedIn?

Taplio

.css-1jgreyo{background-image:linear-gradient(284deg, rgba(39,43,72,1) 0%, rgba(33,47,183,1) 100%);color:transparent;-webkit-background-clip:text;background-clip:text;}David Charlot, PhD, MSEng's Linkedin Analytics

Want to drive more opportunities from LinkedIn?

David Charlot, PhD, MSEng's Linkedin Analytics